JNS-cover.jpgJournal of Neurological Sciences

Vol 345 | No. 1-2 | 15 October 2014 | Pages 1-280

Editorial

Article TitleAuthor(s)Pages

ALS-Plus — Where does it begin, where does it end?

23 July 2014

Nothing vexes and delights the neurologist more than the patient in whom the borders are blurred between diagnostic entities. The era of 'big data' nearly a half-century ago enabled Arthur Hudson to ...

Benjamin Rix Brooks 1-2

Reviews

Article TitleAuthor(s)Pages

Hematoma volume as the major determinant of outcomes after intracerebral hemorrhage

07 July 2014

Abstract: Intracerebral hemorrhage (ICH) is a leading cause of morbidity and mortality, greatly linked to hematoma volume. Understanding the characteristics and size of hematoma is integral to evaluat...

Melissa A. LoPresti, Samuel S. Bruce, Elvis Camacho, Sudkir Kunchala, Byron G. Dubois, Eliza Bruce, Geoff Appelboom, E. Sander Connolly 3-7

CNS-disease affecting the heart: Brain–heart disorders

10 July 2014

Abstract: There are a number of hereditary and non-hereditary central nervous system (CNS) disorders, which directly or indirectly affect the heart (brain–heart disorders). The most well-known of thes...

Josef Finsterer, Karim Wahbi 8-14

Muscle and nerve inflammation in intensive care unit-acquired weakness: A systematic translational review

18 July 2014

Abstract: Background: Intensive care unit-acquired weakness (ICU-AW) is an important complication of critical illness. The main risk factors, sepsis and the systemic inflammatory response syndrome, su...

Esther Witteveen, Luuk Wieske, Camiel Verhamme, Marcus J. Schultz, Ivo N. van Schaik, Janneke Horn 15-25

Assessment of CSF Aβ 42 as an aid to discriminating Alzheimer's disease from other dementias and mild cognitive impairment: A meta-analysis of 50 studies

17 July 2014

Abstract: Mild Alzheimer's disease (AD) is usually difficult to differentiate from other dementias or mild cognitive impairment (MCI). The aim of our study is to evaluate the clinical importance of ce...

Wei Tang, Qiong Huang, Yan Wang, Zheng-Yu Wang, Yu-You Yao 26-36

Association between the ACE I/D polymorphism and risk of ischemic stroke: An updated meta-analysis of 47,026 subjects from 105 case–control studies

21 July 2014

Abstract: Background: The association between the angiotensin-converting enzyme insertion/deletion (ACE I/D) polymorphism and risk of ischemic stroke (IS) remains controversial and ambiguous. To clari...

Jiangyang Zhao, Xue Qin, Shan Li, Zhiyu Zeng 37-47

Original Articles

Article TitleAuthor(s)Pages

Intranasal nerve growth factor attenuates tau phosphorylation in brain after traumatic brain injury in rats

26 June 2014

Abstract: Traumatic brain injury (TBI) is a considerable cause of mild cognitive impairment and dementia. Intranasal administration of nerve growth factor (NGF) has previously been found to improve co...

Qiushi Lv, Wenya Lan, Wenshan Sun, Ruidong Ye, Xiaobing Fan, Minmin Ma, Qin Yin, Yongjun Jiang, Gelin Xu, Jianwu Dai, Ruibing Guo, Xinfeng Liu 48-55

Freezing of gait in Chinese patients with Parkinson Disease

10 July 2014

Abstract: A total of 474 Chinese Parkinson disease (PD) patients were evaluated to explore the prevalence and clinical correlates of freezing of gait (FOG) in this cross-sectional study. Two hundred a...

Ruwei Ou, Xiaoyan Guo, Wei Song, Bei Cao, Jing Yang, Qianqian Wei, Na Shao, Huifang Shang 56-60

A dose–response study of thymosin β4 for the treatment of acute stroke

14 July 2014

Abstract: Background: Thymosin β4 (Tβ4) is a 5K actin binding peptide. Tβ4 improves neurological outcome in a rat model of embolic stroke and research is now focused on optimizing its dose for clinica...

D.C. Morris, Y. Cui, W.L. Cheung, M. Lu, L. Zhang, Z.G. Zhang, M. Chopp 61-67

Impaired mental simulation of specific past and future personal events in non-depressed multiple sclerosis patients

14 July 2014

Abstract: The aims of the present study were (i) to explore autobiographical memory and episodic future thought in multiple sclerosis (MS), using Levine's Autobiographical Interview; (ii) to investiga...

Alexandra Ernst, Frédéric Blanc, Jérôme de Seze, François Sellal, Bruno Chauvin, Liliann Manning 68-74

Age, education and dementia related deaths. The Norwegian Counties Study and The Cohort of Norway

14 July 2014

Abstract: An inverse relationship between educational level and dementia has been reported in several studies. In this study we investigated the relationship between educational level and dementia rel...

Bjørn Heine Strand, Ellen Melbye Langballe, Tor A. Rosness, Astrid Liv Mina Bergem, Knut Engedal, Per Nafstad, Grethe S. Tell, Heidi Ormstad, Kristian Tambs, Espen Bjertness, the GENIDEM-group 75-82

Cardiac diastolic dysfunction predicts in-hospital mortality in acute ischemic stroke with atrial fibrillation

14 July 2014

Abstract: Background: The aim of this study was to identify whether diastolic dysfunction predicts in-hospital death in ischemic stroke patients with atrial fibrillation. Method: We retrospectively an...

Yohei Tateishi, Akira Tsujino, Jumpei Hamabe, Akira Tsuneto, Koji Maemura, Osamu Tasaki, Nobutaka Horie, Tsuyoshi Izumo, Kentaro Hayashi, Izumi Nagata 83-86

The association between post-polio symptoms as measured by the Index of Post-Polio Sequelae and self-reported functional status

21 July 2014

Abstract: Objective: To evaluate the association between self-reported severity of polio sequelae and current functional status among polio survivors. Methods: This was a cross sectional study of 195 ...

Isabella Schwartz, Irina Gartsman, Bella Adler, Yechiel Friedlander, Orly Manor, Hagai Levine, Zeev Meiner 87-91

Relationship between HLA-DRB1* 11/15 genotype and susceptibility to multiple sclerosis in IRAN

18 July 2014

Abstract: Background & objectives: Analysis of the role of different alleles of human leukocyte antigen (HLA) in multiple sclerosis (MS) patients is necessary in many populations and geographical ...

Roya Abolfazli, Sara Samadzadeh, Tayebeh Sabokbar, Bahaadin Siroos, Saeed Azad Armaki, Bahram Aslanbeiki, Mohsen Ghelman, Taher Taheri, Abbas Shakoori 92-96

Functional polymorphisms of the MAO gene with Parkinson disease susceptibility: A meta-analysis

16 July 2014

Abstract: Objective: We carried out a meta-analysis focusing on the relationships between rs1137070 C>T and rs1799836 A>G polymorphisms in the MAO gene as a modifier of Parkinson disease (PD) su...

Yong-Xin Sun, Xiao-Hong Wang, Ai-Hua Xu, Jiu-Han Zhao 97-105

Effects of edaravone on early outcomes in acute ischemic stroke patients treated with recombinant tissue plasminogen activator

18 July 2014

Abstract: Background: We investigated whether edaravone could improve early outcomes in acute ischemic stroke patients treated with recombinant tissue plasminogen activator (rtPA). Methods: We conduct...

Tomoki Wada, Hideo Yasunaga, Ryota Inokuchi, Hiromasa Horiguchi, Kiyohide Fushimi, Takehiro Matsubara, Susumu Nakajima, Naoki Yahagi 106-111

The role of middle latency evoked potentials in early prediction of favorable outcomes among patients with severe ischemic brain injuries

21 July 2014

Abstract: Objective: To explore the role of middle latency evoked potentials (EPs) as predictors for favorable outcome in patients with severe ischemic brain injuries by comparing the prognostic abili...

Yan Zhang, Miao Wang, Ying Ying Su 112-117

ALS-Plus syndrome: Non-pyramidal features in a large ALS cohort

21 July 2014

Abstract: Objective: Autopsy studies show widespread pathology in amyotrophic lateral sclerosis (ALS), but clinical surveys of multisystem disease in ALS are rare. We investigated ALS-Plus syndrome, a...

Leo McCluskey, Shannon Vandriel, Lauren Elman, Vivianna M. Van Deerlin, John Powers, Ashley Boller, Elisabeth McCarty Wood, John Woo, Corey T. McMillan, Katya Rascovsky, Murray Grossman 118-124

Cerebral microbleeds in a multiethnic elderly community: Demographic and clinical correlates

21 July 2014

Abstract: Background: Microbleeds, small perivascular collections of hemosiderin manifested radiologically as hypointensities on gradient-echo magnetic resonance imaging (MRI), are important markers o...

Anne F. Wiegman, Irene B. Meier, Nicole Schupf, Jennifer J. Manly, Vanessa A. Guzman, Atul Narkhede, Yaakov Stern, Sergi Martinez-Ramirez, Anand Viswanathan, José A. Luchsinger, Steven M. Greenberg, Richard Mayeux, Adam M. Brickman 125-130

Automated gait and balance parameters diagnose and correlate with severity in Parkinson disease

21 July 2014

Abstract: Objective: To assess the suitability of instrumented gait and balance measures for diagnosis and estimation of disease severity in PD. Methods: Each subject performed iTUG (instrumented Time...

D. Campbell Dewey, Svjetlana Miocinovic, Ira Bernstein, Pravin Khemani, Richard B. Dewey, Ross Querry, Shilpa Chitnis, Richard B. Dewey 131-138

Nerve safety of tanezumab, a nerve growth factor inhibitor for pain treatment

21 July 2014

Abstract: Objective: To evaluate peripheral nerve safety and clinical efficacy of tanezumab in patients with painful osteoarthritis. Methods: Patients received intravenous tanezumab 5mg, tanezumab 10m...

Mark T. Brown, David N. Herrmann, Mark Goldstein, Aimee M. Burr, Michael D. Smith, Christine R. West, Kenneth M. Verburg, Peter J. Dyck 139-147

Associations of a polymorphism in the intercellular adhesion molecule-1 (ICAM1) gene and ICAM1 serum levels with migraine in a Chinese Han population

21 July 2014

Abstract: Objective: To investigate the associations of a polymorphism in the intercellular adhesion molecule-1 (ICAM1) gene, and ICAM1 serum levels, with migraine and migraine subtypes in a Han Chine...

Qiu He, Xiang Lin, Fengzhi Wang, Jialiang Xu, Zhanxiu Ren, Wei Chen, Xuesha Xing 148-153

Identification and characterization of a novel splice-site mutation in the Wilson disease gene

24 July 2014

Abstract: This study aimed to identify aberrant transcripts of the new splice-site mutation c.3244-2A>C in the Wilson disease (WD) gene (ATPase, Cu++ transporting, beta polypeptide, ATP7B) and disc...

Sheng-Peng Diao, Ming-Fan Hong, Ye-Qing Huang, Zhi-Sheng Wei, Quan-Xi Su, Zhong-Xing Peng, Qing-Yun Yu, Ai-Qun Liu, Jin Chen, Li Hu 154-158

Novel characterization of gait impairments in people with multiple sclerosis by means of the gait profile score

21 July 2014

Abstract: The assessment of gait abnormalities in individuals with multiple sclerosis (MS) represents a key factor in evaluating the effectiveness of rehabilitation treatments. Despite the availabilit...

Massimiliano Pau, Giancarlo Coghe, Claudia Atzeni, Federica Corona, Giuseppina Pilloni, Maria Giovanna Marrosu, Eleonora Cocco, Manuela Galli 159-163

Variability and prognostic relevance of different phenotypes in amyotrophic lateral sclerosis — Data from a population-based registry

21 July 2014

Abstract: Objectives: The clinical spectrum of amyotrophic lateral sclerosis (ALS) is characterized by a considerable variation. Different phenotypes have been described by previous studies. We assess...

Joachim Wolf, Anton Safer, Johannes C. Wöhrle, Frederick Palm, Wilfred A. Nix, Matthias Maschke, Armin J. Grau 164-167

Dynamic MRI testing of the cervical spine has prognostic significance in patients with progressive upper-limb distal weakness and atrophy

21 July 2014

Abstract: Background: The syndrome of isolated progressive upper-limb distal weakness and atrophy results from disease processes affecting lower motor neurons originating in the cervical anterior horn...

Marc Gotkine, Alon Abraham, Vivian E. Drory, Zohar Argov, John Moshe Gomori, Sergiu C. Blumen 168-171

In vivo assessment of white matter damage in neuromyelitis optica: A diffusion tensor and diffusion kurtosis MR imaging study

28 July 2014

Abstract: Background and purpose: In patients with neuromyelitis optica (NMO), damage to extensive regions of normal-appearing WM has been observed. To investigate the possibility that microstructural...

Margareth Cristina Goncalves Kimura, Thomas Martin Doring, Fernanda Cristina Rueda, Gustavo Tukamoto, Emerson Leandro Gasparetto 172-175

The effects of cystatin C and alkaline phosphatase changes on cognitive function 12-months after bariatric surgery

24 July 2014

Abstract: Background: The mechanisms for improved cognitive function post-bariatric surgery are not well understood. Markers of kidney and liver function (i.e., cystatin C and alkaline phosphatase (AL...

Michael L. Alosco, Mary Beth Spitznagel, Gladys Strain, Michael Devlin, Ronald Cohen, Ross D. Crosby, James E. Mitchell, John Gunstad 176-180

Repeated intravenous thrombolysis after recurrent stroke. A case series and review of the literature

25 July 2014

Abstract: Background: The likelihood of severe disability and death increases with each recurrent stroke. Repeated intravenous (IV) thrombolysis remains one of the therapeutic options when secondary p...

Manuel Cappellari, Giuseppe Moretto, Paolo Bovi 181-183

Vitamin D deficiency in patients with primary immune-mediated peripheral neuropathies

28 July 2014

Abstract: Purpose: T cells are important in the immunopathology of immune-mediated peripheral neuropathies (PNP) and activated vitamin D regulates the immune response through increasing the amount of ...

Kristin Elf, Håkan Askmark, Ingela Nygren, Anna Rostedt Punga 184-188

Cardiac involvement in chronic progressive external ophthalmoplegia

30 July 2014

Abstract: Myocardial involvement has not been extensively investigated in mitochondrial myopathies. The aim of the study was to assess the myocardial morpho-functional changes in patients with chronic...

Fabio Galetta, Ferdinando Franzoni, Michelangelo Mancuso, Daniele Orsucci, Leonardo Tocchini, Riccardo Papi, Giuseppe Speziale, Carlo Gaudio, Gabriele Siciliano, Gino Santoro 189-192

Clinical features and neuropsychological profile in vascular parkinsonism

30 July 2014

Abstract: Background: The clinical profile in vascular parkinsonism (VP) patients is well described in the literature, but little is known about the neuropsychological features of this disease. The ai...

Sonia Benítez-Rivero, María J. Lama, Ismael Huertas-Fernández, Paloma Álvarez de Toledo, María T. Cáceres-Redondo, Juan F. Martín-Rodríguez, Fátima Carrillo, Manuel Carballo, Francisco J. Palomar, Pablo Mir 193-197

Association between 12p13 SNP rs11833579 and ischemic stroke in Asian population: An updated meta-analysis

30 July 2014

Abstract: Background: A GWAS found that the single-nucleotide polymorphism rs11833579 near the NINJ2 gene on chromosome 12p13 was associated with an increased risk of ischemic stroke in Caucasians in ...

Ling Wang, Chi Zhao, Qing-xin Xia, Si-jie Qiao 198-201

Trends of hospitalized acute stroke care in Germany from clinical trials to bedside. Comparison of nation-wide administrative data 2008–2012

31 July 2014

Abstract: Promising advances in stroke medicine have been reported recently regarding specialized stroke unit (SU) care, expansion of the time window of iv thrombolysis (IVT), mechanical thrombectomy ...

Christos Krogias, Dirk Bartig, Martin Kitzrow, Ralph Weber, Jens Eyding 202-208

Longitudinally extensive optic neuritis in neuromyelitis optica spectrum disorder

30 July 2014

Abstract: Background: Neuomyelitis optica, sarcoid, and multiple sclerosis can all cause optic neuritis. Further means of distinguishing the causes of optic neuritis among these etiologies would be va...

John H. Pula, Jorge C. Kattah, Bonnie Keung, Huaping Wang, Jennifer Daily 209-212

Individual factors enhance poor health-related quality of life outcome in multiple sclerosis patients. Significance of predictive determinants

30 July 2014

Abstract: Background: Individual factors in multiple sclerosis (MS) patients may modify the reliability of health-related quality of life (HRQOL) assessment. Knowledge of these effects may enable phys...

David Cioncoloni, Iglis Innocenti, Sabina Bartalini, Emiliano Santarnecchi, Simone Rossi, Alessandro Rossi, Monica Ulivelli 213-219

Mitochondrial complex I gene variations; as a potential genetic risk factor in pathogenesis of multiple sclerosis

30 July 2014

Abstract: Background and purpose: Multiple sclerosis (MS) is an autoimmune-mediated inflammatory and debilitating disease of the central nervous system. Several investigations have suggested that the ...

Ahmad Poursadegh Zonouzi, Saeid Ghorbian, Morteza Abkar, Ali Akbar Poursadegh Zonouzi, Ali Azadi 220-223

Acute neurological worsening after Rituximab treatment in patients with anti-MAG neuropathy

04 August 2014

Abstract: Background: Patients with peripheral neuropathy and anti-MAG monoclonal IgM may respond to Rituximab, a humanized monoclonal anti-CD20 antibody. Methods: We report on three patients with per...

Emilie Sala, Florence Robert-Varvat, Stéphane Paul, Jean-Philippe Camdessanché, Jean-Christophe Antoine 224-227

Short Communications

Article TitleAuthor(s)Pages

Retinitis pigmentosa and macular degeneration in a patient with ataxia with isolated vitamin E deficiency with a novel c.717 del C mutation in the TTPA gene

11 July 2014

Abstract: Ataxia with isolated vitamin E deficiency (AVED) is a neurodegenerative disease caused by a mutation in the α-tocopherol transfer protein gene (TTPA). The clinical features of the disease re...

Kazuo Iwasa, Keisuke Shima, Kiyonobu Komai, Yoichiro Nishida, Takanori Yokota, Masahito Yamada 228-230

Efficacy of diflunisal on autonomic dysfunction of late-onset familial amyloid polyneuropathy (TTR Val30Met) in a Japanese endemic area

16 July 2014

Abstract: Objective: To evaluate the long-term efficacy and safety of diflunisal in late-onset familial amyloid polyneuropathy (FAP) in a Japanese endemic area. Methods: Consecutive six FAP patients (...

Ryoichi Takahashi, Kenjiro Ono, Shutaro Shibata, Keiko Nakamura, Junji Komatsu, Yoshihisa Ikeda, Tokuhei Ikeda, Miharu Samuraki, Kenji Sakai, Kazuo Iwasa, Daiki Kayano, Masahito Yamada 231-235

Familial acute necrotizing encephalopathy due to mutation in the RANBP2 gene

21 July 2014

Abstract: Background: Acute necrotizing encephalopathy (ANE) is a rare and severe parainfectious central nervous system disease in which previously healthy children develop rapidly progressive coma fo...

Christian Denier, Laurent Balu, Béatrice Husson, Ghaidaa Nasser, Lydie Burglen, Diana Rodriguez, Pierre Labauge, Laurent Chevret 236-238

Polymyositis in solid organ transplant recipients receiving tacrolimus

08 August 2014

Abstract: Tacrolimus, also known as FK506, is an immunosuppressive agent widely used for the prevention of acute allograft rejection in organ transplantation and for the treatment of immunological dis...

Gaetano Vattemi, Matteo Marini, Marzia Di Chio, Maria Colpani, Valeria Guglielmi, Giuliano Tomelleri 239-243

Clinical usefulness of FDG PET/CT in the detection of unusual central nervous system infections

28 July 2014

Abstract: We report two unusual cases of suppurative meningomyelitis and ventriculitis which were successfully detected by FDG PET/CT. The extent of disease and response to treatment were well-delinea...

Jing-Ren Tseng, Yung-Yueh Su, Ming-Hsun Lee, Ke-Yuan Chen, Shu-Fan Tsai, Tzu-Chen Yen 244-247

Are natural killer cells involved in multiple sclerosis etiology? Evidences from NKp46/NCR1 receptor modulation in an observational study

31 July 2014

Abstract: Natural killer (NK) cells are implicated in many autoimmune diseases but their role in multiple sclerosis (MS) remains still unknown. This study was aimed to evaluate the expression levels o...

Maria Galuppo, Sabrina Giacoppo, Edoardo Sessa, Placido Bramanti, Emanuela Mazzon 248-251

Letters to the Editor

Article TitleAuthor(s)Pages

Impulse control and repetitive behaviors in Parkinson's disease — Are there differences in the relation to dopamine agonist treatment?

11 July 2014

Johanne Hatteland Somme, Juan Carlos Gómez-Esteban, Beatriz Tijero, Koldo Berganzo, Elena Lezcano, Juan Jose Zarranz 252-253

Differential expression of microRNA-206 in the gastrocnemius and biceps brachii in response to CSF from sporadic amyotrophic lateral sclerosis patients

11 July 2014

Rajendrarao Sumitha, Ravinder Jeet Singh Sidhu, Talakad N. Sathyaprabha, Atchayaram Nalini, Trichur R. Raju, Phalguni Anand Alladi 254-256

Acute bilateral radial palsy responsive to intravenous immunoglobulins

14 July 2014

Multifocal motor neuropathy with conduction blocks (MMNCB) is an immune-mediated neuropathy affecting patients at a mean age of 45years. It is characterized by asymmetric purely motor deficits of prog...

Julien Lagarde, Florence Moncharmont, Fatma Bouibede, Thierry Maisonobe 257-259

Bilateral cytotoxic edema of the centrum semiovale in uremic encephalopathy

18 July 2014

Uremic encephalopathy (UE) is a relatively new entity, resulting from a variety of metabolic alterations associated with acute or chronic renal failure. It has a heterogeneous presentation, most often...

Carlos R. Camara-Lemarroy, Hazael Flores-Cantu, Camilo D. Gonzalez-Velazquez, Hector J. Calderon-Hernandez, Alejandra G. Mendoza-Garcia, Hector J. Villareal-Velazquez 260-261

Uhthoff's phenomena and brain MRI suggesting demyelinating lesions: RIS or CIS? A case report

18 July 2014

Uhthoff's phenomenon (UP) is a stereotyped, brief disturbance in neurological functioning triggered by any increase in core body temperature (CBT) . It is related to recurrent fluctuations in neuronal...

Damiano Baroncini, Mauro Zaffaroni, Giorgio Minonzio, Pietro Annovazzi, Silvana M. Baldini, Giancarlo Comi, Angelo Ghezzi 262-264

A pitfall of brain MRI in evaluation of numb chin syndrome: Mandibular MRI should be included to localize lesions

21 July 2014

Numb chin syndrome (NCS) refers to abnormal sensation in the chin and lower lip within the mental nerve distribution. NCS is caused by malignant infiltration of the inferior alveolar nerve or the ment...

Tae-Won Kim, Jeong-Wook Park, Joong-Seok Kim 265-266

Neurolymphomatosis exhibiting repeated exacerbation and remission in both the peripheral and central nervous systems

28 July 2014

The neurolymphomatosis is defined as infiltration of lymphoma and nontumor lymphocytes to the peripheral nervous system . Neurolymphomatosis occurs in 8.5–29% of non-Hodgkin's lymphoma cases . Althoug...

Akio Akagi, Kenjiro Ono, Tsuyoshi Hamaguchi, Miharu Samuraki, Mitsutoshi Nakada, Yukiko Shima, Tetuya Oohata, Masahito Yamada 267-268

SCA 17 phenotype with intermediate triplet repeat number

28 July 2014

Spinocerebellar ataxias are characterized by progressive neurodegeneration and are commonly inherited in an autosomal dominant fashion. Spinocerebellar ataxia 17 (SCA 17) is caused by a heterozygous m...

Heather Herrema, Tom Mikkelsen, Adam Robin, Peter LeWitt, Christos Sidiropoulos 269-270

Clinical, electrophysiological and pathological findings in a patient with Charcot–Marie–Tooth disease 4D caused by the NDRG1 Lom mutation

31 July 2014

Charcot–Marie–Tooth (CMT) disease is a clinically and genetically heterogeneous group of inherited peripheral neuropathies . According to electrophysiological findings, CMT is divided into two main su...

Marco Luigetti, Franco Taroni, Micaela Milani, Alessandra Del Grande, Angela Romano, Giulia Bisogni, Amelia Conte, Ilaria Contaldo, Eugenio Mercuri, Mario Sabatelli 271-273

Predicting the course of aneurysmal subarachnoid hemorrhage with biomarkers: Molecular basis of delayed neurological deterioration

30 July 2014

I have read, with interest, a recently published article in the Journal of the Neurological Sciences by Rodriguez-Rodriguez et al. titled 'Biomarkers of vasospasm development and outcome in aneurysmal...

Dale Ding 274-275

Juvenile-onset parkinsonism with digenic parkin and PINK1 mutations treated with subthalamic nucleus stimulation at 45years after disease onset

04 August 2014

Keiichi Nakahara, Mitsuharu Ueda, Kazumichi Yamada, Tatsuya Koide, Genshin Yoshimochi, Manabu Funayama, Jeong-ho Kim, Shiori Yamakawa, Akira Mori, Yohei Misumi, Eiichiro Uyama, Nobutaka Hattori, Yukio Ando 276-277

Sporadic Creutzfeldt–Jakob disease with mesiotemporal hypermetabolism

04 August 2014

Creutzfeldt–Jakob disease (CJD) is a neurodegenerative prion disease commonly presenting with rapidly progressive dementia. The clinical diagnosis (CJD probable, CJD possible) is made by clinical find...

Philipp Euskirchen, Ralph Buchert, Arend Koch, Walter J. Schulz-Schaeffer, Stephan J. Schreiber, Jan Sobesky 278-280